Assay Detail
Binding
CHEMBL801818
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for the inhibition of SBL-M222C-SMe enzyme.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Lederbergia lenta |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Altering the specificity of subtilisin B. Lentus by combining site-directed mutagenesis and chemical modification
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.19 | 5.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL20726 | — | — | 1 | 5.42 |
| CHEMBL20866 | — | — | 1 | 4.95 |
| CHEMBL20421 | — | — | 1 | - |
| CHEMBL20461 | PHENETHYLBORONIC ACID | — | 1 | - |
| CHEMBL20852 | — | — | 1 | - |
| CHEMBL21485 | PHENYLBORONIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL20726 | — | Ki | = | 3800.0 | nM | 5.42 |
| CHEMBL20866 | — | Ki | = | 11200.0 | nM | 4.95 |
| CHEMBL20421 | — | Ki | = | 153000.0 | nM | - |
| CHEMBL20461 | PHENETHYLBORONIC ACID | Ki | = | 820000.0 | nM | - |
| CHEMBL20852 | — | Ki | = | 139000.0 | nM | - |
| CHEMBL21485 | PHENYLBORONIC ACID | Ki | = | 123000.0 | nM | - |