Assay Detail
Functional
CHEMBL801873
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Tested for the cytotoxicity in SKOV-3 ovarian cell line
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-OV-3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological evaluation of an N10-Psec substituted pyrrolo[2,1-c][1,4]benzodiazepine prodrug.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.01 | 6.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL30238 | — | — | 1 | 6.25 |
| CHEMBL282988 | — | — | 1 | 5.77 |
| CHEMBL281673 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL30238 | — | IC50 | = | 560.0 | nM | 6.25 |
| CHEMBL282988 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL281673 | — | IC50 | > | 25000.0 | nM | - |