Assay Detail
Binding
CHEMBL801965
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Dissociation constant towards SHP 1 receptor-inhibitor complex was determined using PNP as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 6 (CHEMBL3166) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
alpha-bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: structure-Activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.54 | 4.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL105795 | — | — | 1 | 4.54 |
| CHEMBL102756 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL105795 | — | Ki | = | 29000.0 | nM | 4.54 |
| CHEMBL102756 | — | Ki | > | 200000.0 | nM | - |