Assay Detail
Functional
CHEMBL802029
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Cytotoxicity against human ovarian adenocarcinoma (SK-OV-3) cell line using MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-OV-3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antitumor activity of 4-phenyl-1-arylsulfonyl imidazolidinones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.57 | 6.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL39033 | — | — | 1 | 6.25 |
| CHEMBL39830 | — | — | 1 | 5.91 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.38 |
| CHEMBL38709 | — | — | 1 | 5.37 |
| CHEMBL289615 | — | — | 1 | 4.92 |
| CHEMBL7643 | SULOFENUR | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL39033 | — | IC50 | = | 560.0 | nM | 6.25 |
| CHEMBL39830 | — | IC50 | = | 1240.0 | nM | 5.91 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 4150.0 | nM | 5.38 |
| CHEMBL38709 | — | IC50 | = | 4240.0 | nM | 5.37 |
| CHEMBL289615 | — | IC50 | = | 12130.0 | nM | 4.92 |
| CHEMBL7643 | SULOFENUR | IC50 | = | 222900.0 | nM | - |