Assay Detail
Binding
CHEMBL802048
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist binding of L-N6-phenyl-isopropyl)-[3H]adenosine to rat fat
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Expert |
Publication
Adenosine receptors: targets for future drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.48 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL139000 | (R)-PIA | — | 1 | 8.30 |
| CHEMBL45891 | — | — | 1 | 8.15 |
| CHEMBL285819 | — | — | 1 | 8.05 |
| CHEMBL420705 | (S)-PIA | — | 1 | 7.30 |
| CHEMBL275084 | ISOBUTYLMETHYLXANTHINE | — | 1 | 4.70 |
| CHEMBL1355736 | THEOPHYLLINE | 4.0 | 1 | 4.66 |
| CHEMBL113 | CAFFEINE | 4.0 | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL139000 | (R)-PIA | Ki | = | 5.0 | nM | 8.30 |
| CHEMBL45891 | — | Ki | = | 7.0 | nM | 8.15 |
| CHEMBL285819 | — | Ki | = | 9.0 | nM | 8.05 |
| CHEMBL420705 | (S)-PIA | Ki | = | 50.0 | nM | 7.30 |
| CHEMBL275084 | ISOBUTYLMETHYLXANTHINE | Ki | = | 20000.0 | nM | 4.70 |
| CHEMBL1355736 | THEOPHYLLINE | Ki | = | 22000.0 | nM | 4.66 |
| CHEMBL113 | CAFFEINE | Ki | = | 60000.0 | nM | 4.22 |