Assay Detail
Functional
CHEMBL802293
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Compound was tested for potency against human colon carcinoma SW 480 cells in a sulforhodamine B assay.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW480 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
1,4-disubstituted anthracene antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.51 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25336 | BISANTRENE | 3.0 | 1 | 7.05 |
| CHEMBL22696 | — | — | 1 | 6.14 |
| CHEMBL125332 | — | — | 1 | 5.50 |
| CHEMBL287188 | — | — | 1 | 5.30 |
| CHEMBL125698 | — | — | 1 | 4.72 |
| CHEMBL121864 | — | — | 1 | 4.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25336 | BISANTRENE | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL22696 | — | IC50 | = | 720.0 | nM | 6.14 |
| CHEMBL125332 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL287188 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL125698 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL121864 | — | IC50 | = | 44000.0 | nM | 4.36 |