Assay Detail
Functional
CHEMBL802896
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Inhibitory concentration required against SK-BR-3 human breast cancer cell line was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-BR-3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of taxoids 5. Synthesis and evaluation of novel water-soluble prodrugs of a 3'-desphenyl-3'-cyclopropyl analogue of docetaxel.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.65 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL46753 | — | — | 1 | 8.96 |
| CHEMBL3545252 | DOCETAXEL | 4.0 | 1 | 8.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL46753 | — | IC50 | = | 1.1 | nM | 8.96 |
| CHEMBL3545252 | DOCETAXEL | IC50 | = | 4.7 | nM | 8.33 |