Assay Detail
Functional
CHEMBL802978
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Inhibitory activity against sialidase of influenza A
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of tetrasubstituted bicyclo[3.2.1]octenes as potential inhibitors of influenza virus sialidase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.55 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL96712 | NEU5AC2EN | — | 1 | 5.55 |
| CHEMBL154991 | — | — | 1 | 4.10 |
| CHEMBL345872 | — | — | 1 | 4.00 |
| CHEMBL155186 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL96712 | NEU5AC2EN | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL154991 | — | IC50 | = | 80000.0 | nM | 4.10 |
| CHEMBL345872 | — | IC50 | = | 99000.0 | nM | 4.00 |
| CHEMBL155186 | — | IC50 | > | 670000.0 | nM | - |