Assay Detail
Functional
CHEMBL802979
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Inhibitory activity against sialidase of influenza A
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of a tetrasubstituted bicyclo [2.2.2] octane as a potential inhibitor of influenza virus sialidase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.22 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL54758 | — | — | 1 | 6.89 |
| CHEMBL96712 | NEU5AC2EN | — | 1 | 5.55 |
| CHEMBL2112153 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL54758 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL96712 | NEU5AC2EN | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL2112153 | — | IC50 | = | 660000.0 | nM | - |