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Assay Detail

CHEMBL802992

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against influenza virus A(N9) sialidase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism influenza virus a
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis of delta4-beta-D-glucopyranosiduronic acids as mimetics of 2,3-unsaturated sialic acids for sialidase inhibition.
Florio P, Thomson RJ, Alafaci A, Abo S, von Itzstein M.
Bioorg Med Chem Lett (1999) 9 : 2065 -2068
PubMed 10450982 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.73 5.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL96712 NEU5AC2EN 1 5.89
CHEMBL63465 1 5.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL96712 NEU5AC2EN Ki = 1300.0 nM 5.89
CHEMBL63465 Ki = 2700.0 nM 5.57