Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL803286

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition activity against human plasma renin at pH=7.4.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Plasma
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Renin (CHEMBL286)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Protease inhibitors: current status and future prospects.
Leung D, Abbenante G, Fairlie DP.
J Med Chem (2000) 43 : 305 -341
PubMed 10669559 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.96 8.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL113841 ZANKIREN 2.0 1 8.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL113841 ZANKIREN IC50 = 1.1 nM 8.96