Assay Detail
Binding
CHEMBL803318
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Inhibitory activity against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum 3D7 |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Synthesis of 2-fluoronoraristeromycin and its inhibitory activity against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.54 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL129014 | NORARISTEROMYCIN | — | 1 | 6.75 |
| CHEMBL129469 | — | — | 1 | 6.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL129014 | NORARISTEROMYCIN | Ki | = | 180.0 | nM | 6.75 |
| CHEMBL129469 | — | Ki | = | 480.0 | nM | 6.32 |