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Assay Detail

CHEMBL803400

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Binding
Dissociation constant with retinol binding protein was determined
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

HINT predictive analysis of binding between retinol binding protein and hydrophobic ligands.
Marabotti A, Balestreri L, Cozzini P, Mozzarelli A, Kellogg GE, Abraham DJ.
Bioorg Med Chem Lett (2000) 10 : 2129 -2132
PubMed 10999486 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 3 6.99 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL986 RETINOL 4.0 1 7.16
CHEMBL418471 1 7.05
CHEMBL7301 FENRETINIDE 3.0 1 6.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL986 RETINOL Kd = 70.0 nM 7.16
CHEMBL418471 Kd = 90.0 nM 7.05
CHEMBL7301 FENRETINIDE Kd = 170.0 nM 6.77