Assay Detail
Functional
CHEMBL803588
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Inhibitory activity against Selectin E using cell-cell assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Development of potent non-carbohydrate imidazole-based small molecule selectin inhibitors with antiinflammatory activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.61 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL62853 | — | — | 1 | 4.70 |
| CHEMBL302139 | — | — | 1 | 4.52 |
| CHEMBL293171 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL62853 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL302139 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL293171 | — | IC50 | > | 100000.0 | nM | - |