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Assay Detail

CHEMBL804255

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Functional
Evaluated for inhibitory activity against rhinovirus type 4
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism rhinovirus type 4
Confidence 1 — Organism
Curated By Intermediate

Target

rhinovirus B4 (CHEMBL612524)
Type ORGANISM
Organism rhinovirus B4

Publication

Antirhinovirus activity of 6-anilino-9-benzyl-2-chloro-9H-purines.
Kelley JL, Linn JA, Selway JW.
J Med Chem (1990) 33 : 1360 -1363
PubMed 2158561 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 13 5.06 5.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL417662 1 5.35
CHEMBL27294 1 5.29
CHEMBL29938 1 5.26
CHEMBL283490 1 5.24
CHEMBL29955 1 5.19
CHEMBL417851 1 5.17
CHEMBL26199 1 5.11
CHEMBL284406 1 5.08
CHEMBL281707 1 5.08
CHEMBL29399 1 5.06
CHEMBL29437 1 4.85
CHEMBL30218 1 4.07
CHEMBL29441 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL417662 IC50 = 4500.0 nM 5.35
CHEMBL27294 IC50 = 5100.0 nM 5.29
CHEMBL29938 IC50 = 5500.0 nM 5.26
CHEMBL283490 IC50 = 5700.0 nM 5.24
CHEMBL29955 IC50 = 6400.0 nM 5.19
CHEMBL417851 IC50 = 6800.0 nM 5.17
CHEMBL26199 IC50 = 7800.0 nM 5.11
CHEMBL284406 IC50 = 8400.0 nM 5.08
CHEMBL281707 IC50 = 8300.0 nM 5.08
CHEMBL29399 IC50 = 8700.0 nM 5.06
CHEMBL29437 IC50 = 14200.0 nM 4.85
CHEMBL30218 IC50 = 85000.0 nM 4.07
CHEMBL29441 IC50 > 10000.0 nM -