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Assay Detail

CHEMBL804256

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Functional
Evaluated for inhibitory activity against rhinovirus type 5
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism rhinovirus type 5
Confidence 1 — Organism
Curated By Intermediate

Target

rhinovirus B5 (CHEMBL612467)
Type ORGANISM
Organism rhinovirus B5

Publication

Antirhinovirus activity of 6-anilino-9-benzyl-2-chloro-9H-purines.
Kelley JL, Linn JA, Selway JW.
J Med Chem (1990) 33 : 1360 -1363
PubMed 2158561 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 10 5.04 5.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL29938 1 5.25
CHEMBL283490 1 5.12
CHEMBL284406 1 5.07
CHEMBL26199 1 5.02
CHEMBL417851 1 5.00
CHEMBL29437 1 4.79
CHEMBL29955 1 -
CHEMBL27294 1 -
CHEMBL30218 1 -
CHEMBL29441 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL29938 IC50 = 5600.0 nM 5.25
CHEMBL283490 IC50 = 7600.0 nM 5.12
CHEMBL284406 IC50 = 8500.0 nM 5.07
CHEMBL26199 IC50 = 9500.0 nM 5.02
CHEMBL417851 IC50 = 10000.0 nM 5.00
CHEMBL29437 IC50 = 16300.0 nM 4.79
CHEMBL29955 IC50 > 8000.0 nM -
CHEMBL27294 IC50 > 8000.0 nM -
CHEMBL30218 IC50 = 200000.0 nM -
CHEMBL29441 IC50 > 100000.0 nM -