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Assay Detail

CHEMBL805399

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Functional
Inhibition of Rb positive Skut 1B cell proliferation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Cell Type Skut1B
Confidence 1 — Organism
Curated By Expert

Target

Skut1B (CHEMBL614678)
Type CELL-LINE
Organism Homo sapiens

Publication

Identification of selective inhibitors of cyclin dependent kinase 4.
Carini DJ, Kaltenbach RF, Liu J, Benfield PA, Boylan J, Boisclair M, Brizuela L, Burton CR, Cox S, Grafstrom R, Harrison BA, Harrison K, Akamike E, Markwalder JA, Nakano Y, Seitz SP, Sharp DM, Trainor GL, Sielecki TM.
Bioorg Med Chem Lett (2001) 11 : 2209 -2211
PubMed 11514172 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.39 5.39

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL67655 1 5.39

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL67655 IC50 = 4100.0 nM 5.39