Assay Detail
Binding
CHEMBL805617
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Binding affinity against sigma opioid receptor using [3H](+)-3-PPP as radioligand.
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Enantiomeric N-substituted N-normetazocines: a comparative study of affinities at sigma, PCP, and mu opioid receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 6.33 | 7.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2367808 | — | — | 1 | 7.84 |
| CHEMBL2367799 | — | — | 1 | 7.28 |
| CHEMBL2367809 | — | — | 1 | 7.03 |
| CHEMBL2367806 | — | — | 1 | 6.80 |
| CHEMBL2367792 | — | — | 1 | 6.34 |
| CHEMBL2367798 | — | — | 1 | 5.95 |
| CHEMBL2367807 | — | — | 1 | 5.87 |
| CHEMBL2367797 | — | — | 1 | 5.74 |
| CHEMBL2367796 | — | — | 1 | 5.43 |
| CHEMBL2367789 | — | — | 1 | 4.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2367808 | — | Ki | = | 14.5 | nM | 7.84 |
| CHEMBL2367799 | — | Ki | = | 52.5 | nM | 7.28 |
| CHEMBL2367809 | — | Ki | = | 93.7 | nM | 7.03 |
| CHEMBL2367806 | — | Ki | = | 159.0 | nM | 6.80 |
| CHEMBL2367792 | — | Ki | = | 460.0 | nM | 6.34 |
| CHEMBL2367798 | — | Ki | = | 1130.0 | nM | 5.95 |
| CHEMBL2367807 | — | Ki | = | 1340.0 | nM | 5.87 |
| CHEMBL2367797 | — | Ki | = | 1840.0 | nM | 5.74 |
| CHEMBL2367796 | — | Ki | = | 3698.0 | nM | 5.43 |
| CHEMBL2367789 | — | Ki | = | 10600.0 | nM | 4.97 |