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Assay Detail

CHEMBL805755

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of SHP-2 phosphatase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Potent, selective inhibitors of protein tyrosine phosphatase 1B.
Xin Z, Oost TK, Abad-Zapatero C, Hajduk PJ, Pei Z, Szczepankiewicz BG, Hutchins CW, Ballaron SJ, Stashko MA, Lubben T, Trevillyan JM, Jirousek MR, Liu G.
Bioorg Med Chem Lett (2003) 13 : 1887 -1890
PubMed 12749891 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.14 4.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL55243 1 4.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL55243 Ki = 73170.0 nM 4.14