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Assay Detail

CHEMBL805970

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant human TNF-alpha converting enzyme
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Publication

Structure--activity relationships of azasugar-based MMP/ADAM inhibitors.
Moriyama H, Tsukida T, Inoue Y, Kondo H, Yoshino K, Nishimura S.
Bioorg Med Chem Lett (2003) 13 : 2737 -2740
PubMed 12873504 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.64 8.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL61193 1 8.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL61193 Ki = 2.3 nM 8.64