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Assay Detail

CHEMBL806261

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of [3H]ATRA-Hl60 binding to Retinoic acid receptor gamma
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Retinoic acid receptor gamma (CHEMBL2003)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Novel retinoic acid receptor alpha agonists: syntheses and evaluation of pyrazole derivatives.
Kikuchi K, Hibi S, Yoshimura H, Tai K, Hida T, Tokuhara N, Yamauchi T, Nagai M.
Bioorg Med Chem Lett (2000) 10 : 619 -622
PubMed 10762038 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.30 9.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL38 TRETINOIN 4.0 1 9.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL38 TRETINOIN IC50 = 0.5 nM 9.30