Assay Detail
Binding
CHEMBL806299
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Binding affinity for human receptor subtype hSSTR2
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Modulation of receptor and receptor subtype affinities using diastereomeric and enantiomeric monosaccharide scaffolds as a means to structural and biological diversity. A new route to ether synthesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 5.68 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL282129 | — | — | 1 | 6.22 |
| CHEMBL285333 | — | — | 1 | 6.10 |
| CHEMBL282618 | — | — | 1 | 5.75 |
| CHEMBL29311 | — | — | 1 | 5.58 |
| CHEMBL282803 | — | — | 1 | 5.57 |
| CHEMBL281200 | — | — | 1 | 5.51 |
| CHEMBL28824 | — | — | 1 | 5.34 |
| CHEMBL29102 | — | — | 1 | 5.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL282129 | — | Ki | = | 600.0 | nM | 6.22 |
| CHEMBL285333 | — | Ki | = | 800.0 | nM | 6.10 |
| CHEMBL282618 | — | Ki | = | 1800.0 | nM | 5.75 |
| CHEMBL29311 | — | Ki | = | 2600.0 | nM | 5.58 |
| CHEMBL282803 | — | Ki | = | 2700.0 | nM | 5.57 |
| CHEMBL281200 | — | Ki | = | 3100.0 | nM | 5.51 |
| CHEMBL28824 | — | Ki | = | 4600.0 | nM | 5.34 |
| CHEMBL29102 | — | Ki | = | 4600.0 | nM | 5.34 |