Assay Detail
Binding
CHEMBL806346
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Src tyrosine kinase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Proto-oncogene tyrosine-protein kinase Src (CHEMBL267) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The development of novel and selective p56lck tyrosine kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.90 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL84807 | — | — | 1 | 6.34 |
| CHEMBL84808 | — | — | 1 | 5.46 |
| CHEMBL82560 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL84807 | — | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL84808 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL82560 | — | IC50 | > | 50000.0 | nM | - |