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Assay Detail

CHEMBL806428

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Src kinase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Proto-oncogene tyrosine-protein kinase Src (CHEMBL267)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

7-Alkoxy-4-phenylamino-3-quinolinecar-bonitriles as dual inhibitors of Src and Abl kinases.
Boschelli DH, Wang YD, Johnson S, Wu B, Ye F, Barrios Sosa AC, Golas JM, Boschelli F.
J Med Chem (2004) 47 : 1599 -1601
PubMed 15027848 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.85 5.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL290398 1 5.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL290398 IC50 = 1400.0 nM 5.85