Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL806598

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity for human receptor subtype hSSTR5.
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Somatostatin receptor type 5 (CHEMBL1792)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Modulation of receptor and receptor subtype affinities using diastereomeric and enantiomeric monosaccharide scaffolds as a means to structural and biological diversity. A new route to ether synthesis.
Hirschmann R, Hynes J, Cichy-Knight MA, van Rijn RD, Sprengeler PA, Spoors PG, Shakespeare WC, Pietranico-Cole S, Barbosa J, Liu J, Yao W, Rohrer S, Smith AB.
J Med Chem (1998) 41 : 1382 -1391
PubMed 9554871 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 7 5.49 5.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL282129 1 5.89
CHEMBL29102 1 5.52
CHEMBL282803 1 5.47
CHEMBL282618 1 5.43
CHEMBL29311 1 5.41
CHEMBL28824 1 5.40
CHEMBL281200 1 5.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL282129 Ki = 1300.0 nM 5.89
CHEMBL29102 Ki = 3000.0 nM 5.52
CHEMBL282803 Ki = 3400.0 nM 5.47
CHEMBL282618 Ki = 3700.0 nM 5.43
CHEMBL29311 Ki = 3900.0 nM 5.41
CHEMBL28824 Ki = 4000.0 nM 5.40
CHEMBL281200 Ki = 5100.0 nM 5.29