Assay Detail
Binding
CHEMBL806659
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Inhibition of [3H]9-cis-RA binding to Retinoid X receptor RXR beta
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and structure-activity relationships of potent retinoid X receptor ligands
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 7.56 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL80236 | — | — | 1 | 8.22 |
| CHEMBL310047 | — | — | 1 | 8.00 |
| CHEMBL312395 | — | — | 1 | 8.00 |
| CHEMBL75814 | — | — | 1 | 8.00 |
| CHEMBL311113 | — | — | 1 | 7.96 |
| CHEMBL312737 | — | — | 1 | 7.60 |
| CHEMBL79234 | — | — | 1 | 7.44 |
| CHEMBL312233 | — | — | 1 | 6.60 |
| CHEMBL80424 | — | — | 1 | 6.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL80236 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL310047 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL312395 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL75814 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL311113 | — | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL312737 | — | Ki | = | 25.0 | nM | 7.60 |
| CHEMBL79234 | — | Ki | = | 36.0 | nM | 7.44 |
| CHEMBL312233 | — | Ki | = | 252.0 | nM | 6.60 |
| CHEMBL80424 | — | Ki | = | 556.0 | nM | 6.25 |