Assay Detail
Binding
CHEMBL807044
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Tested for binding affinity at human Somatostatin receptor type 4 using ([3-125I-Tyr11)]-SRIF-14 as the radioligand
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Effects of heterocyclic aromatic substituents on binding affinities at two distinct sites of somatostatin receptors. Correlation with the electrostatic potential of the substituents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 6.12 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL266004 | — | — | 1 | 6.58 |
| CHEMBL291474 | — | — | 1 | 6.44 |
| CHEMBL55298 | — | — | 1 | 6.24 |
| CHEMBL53440 | — | — | 1 | 6.17 |
| CHEMBL292906 | — | — | 1 | 6.05 |
| CHEMBL56181 | — | — | 1 | 5.98 |
| CHEMBL293114 | — | — | 1 | 5.92 |
| CHEMBL294830 | — | — | 1 | 5.90 |
| CHEMBL282618 | — | — | 1 | 5.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL266004 | — | Ki | = | 260.0 | nM | 6.58 |
| CHEMBL291474 | — | Ki | = | 360.0 | nM | 6.44 |
| CHEMBL55298 | — | Ki | = | 570.0 | nM | 6.24 |
| CHEMBL53440 | — | Ki | = | 680.0 | nM | 6.17 |
| CHEMBL292906 | — | Ki | = | 890.0 | nM | 6.05 |
| CHEMBL56181 | — | Ki | = | 1040.0 | nM | 5.98 |
| CHEMBL293114 | — | Ki | = | 1200.0 | nM | 5.92 |
| CHEMBL294830 | — | Ki | = | 1260.0 | nM | 5.90 |
| CHEMBL282618 | — | Ki | = | 1650.0 | nM | 5.78 |