Assay Detail
Binding
CHEMBL807588
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Binding affinity against sigma 2 opioid receptor using 3[H]-DTG in the presence of dextrallorphan as radioligand
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Expert |
Publication
A sigma-1 receptor selective analogue of BD1008. A potential substitute for (+)-opioids in sigma receptor binding assays.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.95 | 8.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL20377 | — | — | 1 | 8.09 |
| CHEMBL60542 | (+)-PENTAZOCINE | — | 1 | 5.81 |
| CHEMBL53649 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL20377 | — | Ki | = | 8.1 | nM | 8.09 |
| CHEMBL60542 | (+)-PENTAZOCINE | Ki | = | 1542.0 | nM | 5.81 |
| CHEMBL53649 | — | Ki | > | 10000.0 | nM | - |