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Assay Detail

CHEMBL807905

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against tachykinin receptor 1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Substance-P receptor (CHEMBL249)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

From hit to lead. Analyzing structure-profile relationships.
Poulain R, Horvath D, Bonnet B, Eckhoff C, Chapelain B, Bodinier MC, Déprez B.
J Med Chem (2001) 44 : 3391 -3401
PubMed 11585444 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.08 6.08

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL113956 1 6.08

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL113956 IC50 = 839.0 nM 6.08