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Assay Detail

CHEMBL808439

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity of [125I]T4 to rat liver nuclear extract at a dose of 25 ug/Kg
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Polychlorinated biphenyls and related compound interactions with specific binding sites for thyroxine in rat liver nuclear extracts.
McKinney J, Fannin R, Jordan S, Chae K, Rickenbacher U, Pedersen L.
J Med Chem (1987) 30 : 79 -86
PubMed 3100800 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.25 9.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL30327 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN 1 9.25

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL30327 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN Kd = 0.56 nM 9.25