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Assay Detail

CHEMBL808445

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for inhibition against tissue factor.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitors.
Duncia JV, Santella JB, Higley CA, VanAtten MK, Weber PC, Alexander RS, Kettner CA, Pruitt JR, Liauw AY, Quan ML, Knabb RM, Wexler RR.
Bioorg Med Chem Lett (1998) 8 : 775 -780
PubMed 9871540 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 5.86 6.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2373367 1 6.17
CHEMBL2373345 1 5.55
CHEMBL2373400 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2373367 Ki = 670.0 nM 6.17
CHEMBL2373345 Ki = 2800.0 nM 5.55
CHEMBL2373400 Ki > 10000.0 nM -