Assay Detail
Functional
CHEMBL809094
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for functional activation to [86Rb+] efflux From human medulloblastoma cell line TE671 expressing recombinant alpha-1-beta-1-gamma delta receptors.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.44 | 4.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL430497 | TEBANICLINE | 2.0 | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL430497 | TEBANICLINE | EC50 | = | 36000.0 | nM | 4.44 |