Assay Detail
Binding
CHEMBL809496
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Inhibition of labeled SP total binding against human Tachykinin receptor 1 expressed in astrocytoma UC11MG cells by the second binding component
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | UC11MG |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A non-peptide NK1 receptor agonist showing subpicomolar affinity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.69 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL24829 | — | — | 1 | 7.96 |
| CHEMBL282853 | — | — | 1 | 5.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL24829 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL282853 | — | IC50 | = | 3900.0 | nM | 5.41 |