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Assay Detail

CHEMBL809581

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Src kinase at 100 nM ATP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Proto-oncogene tyrosine-protein kinase Src (CHEMBL267)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibitors of src tyrosine kinase: the preparation and structure-activity relationship of 4-anilino-3-cyanoquinolines and 4-anilinoquinazolines.
Wang YD, Miller K, Boschelli DH, Ye F, Wu B, Floyd MB, Powell DW, Wissner A, Weber JM, Boschelli F.
Bioorg Med Chem Lett (2000) 10 : 2477 -2480
PubMed 11078204 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.47 7.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL81073 1 7.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL81073 IC50 = 34.0 nM 7.47