Assay Detail

CHEMBL809683

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of thromboxane A2 synthetase

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

Thromboxane-A synthase (CHEMBL4028) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

Thromboxane-A synthase (CHEMBL4028) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Thromboxane-A synthase

CHEMBL4028

Anchored from Assay target.

Protein identity Thromboxane-A synthase

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Oryctolagus cuniculus
Confidence	8 — Homologous single protein target
Curated By	Autocuration

Target

Thromboxane-A synthase (CHEMBL4028) ↗

Type	SINGLE PROTEIN
Organism	Rattus norvegicus

Publication

Synthesis and thromboxane synthetase inhibitory activity of di- or tetrahydrobenzo[b]thiophenecarboxylic acid derivatives.

Amemiya Y, Terada A, Wachi K, Miyazawa H, Hatakeyama N, Matsuda K, Oshima T.
J Med Chem (1989) 32 : 1265 -1272
PubMed 2724299 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.97	6.97

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL267473	DAZOXIBEN	2.0	1	6.97

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL267473	DAZOXIBEN	IC50	=	106.0	nM	6.97