Assay Detail
Binding
CHEMBL809689
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Tested for specific binding of radioligand [3H]U-46619 to thromboxane A2 /prostaglandin H2 receptor in guinea pig washed platelets
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Dibenzoxepin derivatives: thromboxane A2 synthase inhibition and thromboxane A2 receptor antagonism combined in one molecule.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.25 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL289076 | — | — | 1 | 6.92 |
| CHEMBL26820 | (E)-ISBOGREL | — | 1 | 5.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL289076 | — | Ki | = | 120.0 | nM | 6.92 |
| CHEMBL26820 | (E)-ISBOGREL | Ki | = | 2700.0 | nM | 5.57 |