Assay Detail
Binding
CHEMBL809909
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cellular thymidylate synthase activity of human leukemia cell line(CCRF-CEM).
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of aromatic amino acid phosphoramidates of 5-fluoro-2'-deoxyuridine and 1-beta-arabinofuranosylcytosine: evidence of phosphoramidase activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.51 | 5.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL96148 | — | — | 2 | 5.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL96148 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL96148 | — | IC50 | = | 190000.0 | nM | - |