Assay Detail
Binding
CHEMBL810139
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity against human cloned Tachykinin receptor 1 expressed in MEL cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | MEL |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery of novel, orally active dual NK1/NK2 antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.76 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL129683 | — | — | 1 | 10.00 |
| CHEMBL330366 | — | — | 1 | 9.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL129683 | — | Ki | = | 0.1 | nM | 10.00 |
| CHEMBL330366 | — | Ki | = | 0.3 | nM | 9.52 |