Assay Detail
Functional
CHEMBL810149
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Evaluated for its concentration at which 50% of maximal stimulation of phosphoinositide turnover was observed
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of a novel 11a-homo (cyclohexyl) prostaglandin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.18 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2220404 | CLOPROSTENOL | 2.0 | 1 | 9.00 |
| CHEMBL815 | DINOPROST | 4.0 | 1 | 7.64 |
| CHEMBL323591 | — | — | 1 | 6.50 |
| CHEMBL428794 | — | — | 1 | 5.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2220404 | CLOPROSTENOL | EC50 | = | 1.0 | nM | 9.00 |
| CHEMBL815 | DINOPROST | EC50 | = | 23.0 | nM | 7.64 |
| CHEMBL323591 | — | EC50 | = | 319.0 | nM | 6.50 |
| CHEMBL428794 | — | EC50 | = | 2750.0 | nM | 5.56 |