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Assay Detail

CHEMBL810833

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Binding
Inhibitory activity against Serum amine oxidase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives.
Manna F, Chimenti F, Bolasco A, Secci D, Bizzarri B, Befani O, Turini P, Mondovi B, Alcaro S, Tafi A.
Bioorg Med Chem Lett (2002) 12 : 3629 -3633
PubMed 12443791 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 4 4.63 5.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL120717 1 5.26
CHEMBL121432 1 5.00
CHEMBL331009 1 4.24
CHEMBL331650 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL120717 Ki = 5500.0 nM 5.26
CHEMBL121432 Ki = 10000.0 nM 5.00
CHEMBL331009 Ki = 57000.0 nM 4.24
CHEMBL331650 Ki = 100000.0 nM 4.00