Assay Detail
Binding
CHEMBL811713
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration binding towards TR-beta-1 in E25B2 cells (agonistic activity)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | E25B2 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TR beta subtype-selective thyromimetics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.21 | 7.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL125946 | — | — | 1 | 7.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL125946 | — | EC50 | = | 62.0 | nM | 7.21 |