Assay Detail
Functional
CHEMBL812677
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Inhibition of calpain-mediated pp60src degradation in platelets
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of novel piperidine carboxamide derived calpain inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.96 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL423112 | — | — | 1 | 6.16 |
| CHEMBL69715 | — | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL423112 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL69715 | — | IC50 | = | 1800.0 | nM | 5.75 |