Assay Detail
Functional
CHEMBL812744
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Concentration to inhibit cell proliferation in U 937 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-937 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological evaluation of MC 1357, a new 20-epi-23-oxa-1,25-dihydroxy-vitamin D3 analogue with potent non-classical effects
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.50 | 11.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL293146 | — | — | 1 | 11.00 |
| CHEMBL846 | CALCITRIOL | 4.0 | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL293146 | — | IC50 | = | 0.01 | nM | 11.00 |
| CHEMBL846 | CALCITRIOL | IC50 | = | 10.0 | nM | 8.00 |