Assay Detail
Binding
CHEMBL812904
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for inhibition of V-ATPase from Chicken osteoclasts (cOc)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Gallus gallus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
5-(5,6-Dichloro-2-indolyl)-2-methoxy-2,4-pentadienamides: novel and selective inhibitors of the vacuolar H+-ATPase of osteoclasts with bone antiresorptive activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290814 | BAFILOMYCIN A1 | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290814 | BAFILOMYCIN A1 | IC50 | = | 100.0 | nM | 7.00 |