Assay Detail
Functional
CHEMBL813244
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Tested for the inhibition of prostromelysin activation with no preincubation period
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Heteroaryl-fused 2-phenylisothiazolone inhibitors of cartilage breakdown.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.25 | 4.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL104863 | — | — | 1 | 4.28 |
| CHEMBL104611 | — | — | 1 | 4.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL104863 | — | IC50 | = | 53000.0 | nM | 4.28 |
| CHEMBL104611 | — | IC50 | = | 62000.0 | nM | 4.21 |