Assay Detail
Binding
CHEMBL813252
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Binding affinity of compound to the stromelysin-1 catalytic domain at pH 6.7, 22 degree C
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Stereoselective binding of an enantiomeric pair of stromelysin-1 inhibitors caused by conformational entropy factors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.65 | 7.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL43152 | — | — | 1 | 7.12 |
| CHEMBL42420 | — | — | 1 | 6.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL43152 | — | Kd | = | 76.6 | nM | 7.12 |
| CHEMBL42420 | — | Kd | = | 679.0 | nM | 6.17 |