Assay Detail
Binding
CHEMBL813599
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against human ovarian cancer cell (A2780 cells) Telomerase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | A2780 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A novel inhibitor of human telomerase derived from 10H-indolo[3,2-b]quinoline.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.98 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL292475 | — | — | 1 | 5.16 |
| CHEMBL292124 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL292475 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL292124 | — | IC50 | = | 16000.0 | nM | 4.80 |