Assay Detail
Functional
CHEMBL814073
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Inhibition of gamma radiation-induced lipid peroxidation in liposomes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Horseradish peroxidase inhibition and antioxidant activity of ebselen and related organoselenium compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.24 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51085 | EBSELEN | 3.0 | 1 | 4.60 |
| CHEMBL376704 | — | — | 1 | 4.12 |
| CHEMBL220461 | — | — | 1 | 4.00 |
| CHEMBL374863 | EBSELEN DITELLURIDE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51085 | EBSELEN | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL376704 | — | IC50 | = | 75000.0 | nM | 4.12 |
| CHEMBL220461 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL374863 | EBSELEN DITELLURIDE | IC50 | = | 175000.0 | nM | - |