Assay Detail
Binding
CHEMBL814272
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Ability to inhibit formation of the TatTAR complex by binding to the closing GC or CG base pair and adjacent nucleotides of loops in the TAR RNA.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Inhibition of the U1A-RNA complex by an aminoacridine derivative.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.83 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL320369 | — | — | 1 | 5.00 |
| CHEMBL97338 | — | — | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL320369 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL97338 | — | IC50 | = | 22000.0 | nM | 4.66 |