Assay Detail
Binding
CHEMBL814360
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Binding affinity towards Urokinase-type plasminogen activator
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Urokinase-type plasminogen activator (CHEMBL3286) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Fragment-based drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.07 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL103043 | — | — | 1 | 7.52 |
| CHEMBL117368 | — | — | 1 | 6.43 |
| CHEMBL119647 | — | — | 1 | 4.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL103043 | — | Ki | = | 30.0 | nM | 7.52 |
| CHEMBL117368 | — | Ki | = | 370.0 | nM | 6.43 |
| CHEMBL119647 | — | Ki | = | 56000.0 | nM | 4.25 |